| Good morning, it is Tuesday, August 27, and we're covering Why Harris wants to unmute Trump, Cannabis Revealed to Have Anti-Aging Effect in The Brains of Mice, a cost of living update & much more!! First time reading? | | American Fact of the Day! | Absolutely! On August 27, 1962, the iconic American rock band The Beach Boys released their album Surfin' Safari. This album was one of their early successes and helped establish their signature sound of surf rock, capturing the carefree spirit of the Californian surf culture and propelling the band into the spotlight. | | Breaking Updates | | Cannabis Revealed to Have Anti-Aging Effect in The Brains of Mice | A new study has found that tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis, can reverse conventional signs of brain aging in mice. This research, conducted by teams from Germany and Israel, builds on existing knowledge about the endocannabinoid system and its links to cognitive decline. The study demonstrated that THC affects brain aging through a signaling pathway involving the mTOR protein, which regulates cell metabolism and the metabolome. Specifically, THC treatment enhanced mTOR activity in the brain and boosted the production of proteins necessary for new synapse formation, while also reducing mTOR activity in fat tissue similar to the effects of a calorie-restricted diet. | These findings suggest that THC has the potential to both improve cognitive functions and exert anti-aging effects. The study used both young and older mice to show that THC enhances brain health by increasing energy and synaptic protein production and decreasing mTOR activity in peripheral tissues. While these results are promising, indicating that THC might delay the onset of dementia and improve brain function, further research in humans is needed. The dual effects on mTOR signaling and the metabolome could potentially lead to new treatments for maintaining brain health in aging, but it is important to balance these benefits with the known risks associated with cannabis use. | Read More Here |
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| Why Harris wants to unmute Trump | In the upcoming debate on September 10, Kamala Harris is pushing for an open-mic format to ensure that Donald Trump has the opportunity to speak freely. This move contrasts with the muted microphone rule from the June debate between President Biden and Trump, which was intended to curb Trump's interruptions. Harris's campaign believes that allowing Trump to speak without restrictions could lead to self-sabotage and provide a chance to showcase Harris's ability to handle his contentious style. | Trump's team is resisting the open-mic proposal, though Trump himself has indicated that he is not opposed to losing the mute button. This debate is viewed as a crucial opportunity for both candidates: Harris aims to demonstrate strength and control, while Trump seeks to recover momentum after Biden's withdrawal and capitalize on Harris's perceived vulnerability. | Harris's debate strategy echoes her famous 2020 line to Mike Pence, "Mr. Vice President, I'm speaking," which became a viral moment highlighting her ability to assert herself. The debate's format reflects broader strategic battles, with Harris hoping that an open mic will highlight Trump's shortcomings and reinforce her campaign's message of moving beyond divisive politics. | Read more updates here | | | American Sports & Culture |  | CeeDee Lamb's extension answers the easier question for Cowboys. But Dak Prescott represents a trickier issue. | Dallas paid big money to its best receiver. But the hard work is far from over as Prescott's expiring contract still looms over the approaching season. |
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|  | US Open: Novak Djokovic starts title defense with dominant win as he eyes 25th Grand Slam championship | Novak Djokovic is fresh off his gold medal win at the Paris Olympics earlier this summer. |
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|  | 'How did Florida end up there?': The stakes are high for Billy Napier and the Gators | The Florida coach has overhauled the program, but on-field results haven't followed. Will that change this season? |
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| American Business & Markets |  | Housing affordability in America is finally improving. Not so much in these cities | With the Federal Reserve all but confirmed to cut interest rates next month, there is finally some light at the end of the tunnel for Americans grappling with the most unaffordable housing market in decades. But the old saying that "real estate is local" still rings painfully true. |
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|  | If you don't own Nvidia stock, you are missing a revolution, tech investor says | Wall Street is bracing for another bull run in darling Nvidia. |
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|  | NFL expected to vote in favor of private equity ownership, CNBC reports | The NFL's 32 owners are to vote at a special league meeting in Eagan, Minnesota, according to CNBC, and the private equity firms intend to commit $12 billion in capital, to be raised inclusive of leverage. The NFL is the only major North American sports league that prohibits private equity ownership in a franchise. The NBA, NHL, Major League Baseball and Major League Soccer allow their teams to sell a maximum of 30% of equity to a fund. |
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| | American Politics |  | Judge blocks 'parole in place' program for immigrant spouses of US citizens | Biden's program allowed undocumented spouses to remain in the country while seeking permanent residency |
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|  | Gen. McMaster says Trump bears some responsibility for chaotic Afghanistan withdrawal | Retired Lt. Gen. H.R. McMaster, who served as national security adviser under former President Donald Trump, said Monday his onetime boss bears some responsibility for the US' chaotic withdrawal from Afghanistan in 2021. |
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|  | Tim Walz and Kristi Noem once had a warm working relationship. Now it's gone ice-cold | These days, the only thing Minnesota Gov. Tim Walz and South Dakota Gov. Kristi Noem seem to have in common is that they're both former-members-of-Congress-turned-Midwestern-governors. |
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